Thanks to everyone who has replied. I'm a guitarist (boo!) who works in IT (boo!?) so VSTi is something new to me - basically, if I can't stamp on a piece of equipment to make my guitar sound "wooshy" then I'm stuck - so all of your input has been excellent. I tried 32-bit Reaper and yes - my VSTi all appeared and made an appalling noise. Appalling, because I'm a guitarist who thinks that playing "Chopsticks" on a keyboard is the mark of a particularly dextrous genius, not because the software wasn't working properly... I upgraded my PC to 8Gb RAM, so it seems that Reaper will have to run in the 32-bit address space and I'll have a few gig left over for... er... printing? Anyways - thanks to everyone who responded and thanks for your help. Reaper is still ace, though - however many bits it uses.